What do you do when you wake up and realize you have been the villain all along? After years of working for CIRCE, Dr. Holly Eva Foster is beginning to realize why her patients have been dying off: she's killing them, but she doesn't know why. Meanwhile, following a devastating ambush and life-or-death surgery, the Padre discovers that his Packmates and colleagues suddenly revile and distrust him. Watching their behaviour degrade from bizarre to brutal, the Padre escapes, only to run into the arms of his least likely allies: enemies of CIRCE. For the sake of all humanity and other-kind, Eva and the Padre must risk their lives-and their minds-to rebel against one creature's well-intended quest: the annihilation of her own kind.